Gliclazide impurity F: N-[(perhydro­cyclo­penta­[c]pyrrol-2-yl)amino­carbon­yl]-o-toluene­sulfonamide

摘要

The title compound, C15H21N3O3S, is known to be an impurity of gliclazide [systematic name: N-(hexa­hydro-1H-cyclopenta[c]pyrrol-2-ylcarbamo­yl)-4-methyl­benzene­sulfonamide], a sul­fonyl­urea anti­diabetic drug. Gliclazide has a p-tolyl group substituting the sulfonamide functionality, while the title mol­ecule contains an o-tolyl group. Both five-membered fused rings adopt envelope conformations. In the crystal, N—H⋯O hydrogen bonds are formed between HN(C=O)NH groups, building centrosymmetric dimers. These dimers are further linked through N—H⋯O(sulfon­yl) contacts, forming chains in [100].